Right-clicking it you want to 'uninstall the device'. In the Windows device manager, you will probably find an entry for your Epson scanner. The device manager is amongst those in the upper section. The keyboard shortcut WIN+X will call a text menu on Windows 10 and 11 providing you with a range of helpful links.
Make sure the scanner is connected and powered on. This article will help you to reinstall both, TWAIN device driver and SilverFast, when you are working on a Microsoft Windows computer. Often times when SilverFast is not able to detect an Epson scanner it will put out a 'driver missing' notification error message.